The NHGRI Genome Sequencing Program Analysis Centers (GSPAC) are a collaborative initiative that will undertake computational analyses of the data produced by the NHGRI Genome Sequencing Program to extract genomic and biological knowledge.
The goals of the GSPAC are to:
- Undertake novel, investigator-initiated analyses that will cut across the individual GSP projects
- Develop improved or novel analyses and methods for all non-automated aspects of characterizing sequence variants in the data, including:
- Identification of associations between variants and disease phenotypes
- Analyses using existing functional data to leverage associations and/or make functional inferences
- Study design improvements
- Work together with the other GSP components on cross-program analyses:
- Defining the point at which a common disease/rare variant genome sequencing study is “comprehensive” or complete,
- developing specifications for sample sets that could serve as common controls for common disease genome sequencing studies
The currently funded GSPACs are at Harvard University School of Public Health , Vanderbilt University School of Medicine , and a cross-institutional center at Icahn School of Medicine at Mount Sinai , Stanford School of Medicine , and University of California at San Francisco School of Pharmacy.
Date last modified: Fri, 09/18/2020 - 09:59